Ifosfamide Injection

Taj-Ando-Ifosfamide Injection
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What is Ifosfamide Injection?

Ifosfamide is a cytotoxic drug or anti-cancer drug.
It is used to treat lots of different cancers.
Ifosfamide is often used together with other anti-cancer drugs or radiotherapy.

Treats certain types of cancer in combination with other medicines.
Ifosfamide and mesna is an antineoplastic and urinary protectant combination.
It works by stopping the growth of certain cancers and by lowering the risk of bleeding in your bladder

Ifosfamide is used in combination with other medications to treat cancer of the testicles that has not improved or that has worsened after treatment with other medications or radiation therapy.
Ifosfamide is in a class of medications called alkylating agents.
It works by slowing or stopping the growth of cancer cells in your body.Ifosfamide Injection – Taj Ando Pharmaceuticals, South Africa | It is used to treat lots of different cancers.Ifosfamide is often used together with other anti-cancer drugs or radiotherapy.Treats certain types of cancer in combination with other medicines.Ifosfamide and mesna is an antineoplastic and urinary protectant combination.
Ifosfamide Injection – Taj Ando Pharmaceuticals, South Africa | It is used to treat lots of different cancers.Ifosfamide is often used together with other anti-cancer drugs or radiotherapy.Treats certain types of cancer in combination with other medicines.Ifosfamide and mesna is an antineoplastic and urinary protectant combination.

Special Precautions

Before receiving ifosfamide,

  • tell your doctor and pharmacist if you are allergic to ifosfamide.
  • Ask your pharmacist for a list of the ingredients.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins and nutritional supplements you are receiving or plan to take.
  • Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • Other medications may also interact with ifosfamide, so be sure to tell your doctor about all the medications you are receiving, even those that do not appear on this list.
  • tell your doctor what herbal products you are receiving.
  • tell your doctor if you have previously received treatment with other chemotherapy medications or if you have previously received radiation therapy.
  • Also tell your doctor if you have or have ever had heart, kidney, or liver disease.
  • you should know that ifosfamide may slow the healing of wounds.
  • you should know that ifosfamide may interfere with the normal menstrual cycle (period) in women and may stop sperm production in men.
  • Ifosfamide may cause permanent infertility (difficulty becoming pregnant)
  • Women who are pregnant or breast-feeding should tell their doctors before they begin receiving this drug.
  • You should not become pregnant or breast-feed while you are receiving ifosfamide.
  • Use a reliable method of birth control to prevent pregnancy while you are receiving ifosfamide and for 6 months after treatments.
  • If you are male, you and your female partner should continue to use birth control for 6 months after you stop receiving ifosfamide injection.
  • If you become pregnant while receiving ifsofamide, call your doctor immediately.
  • Ifosfamide may harm the fetus.

Side Effects
Ifosfamide may cause side effects.
Tell your doctor if any of these symptoms are severe or do not go away:
• nausea
• vomiting
• loss of appetite
• diarrhea
• sores in the mouth and throat
• hair loss
• general feeling of pain and tiredness

Some side effects can be serious.
If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:
• swelling, redness, and pain in the place where the medication was injected
• rash
• itching
• difficulty breathing or swallowing
• shortness of breath
• wheezing
• irregular heartbeat
• chest pain
• hoarseness
• yellowing of the skin or eyes

Ifosfamide may increase the risk that you will develop other cancers.
Talk to your doctor about the risks of receiving ifosfamide injection.
Ifosfamide may cause other side effects.
Call your doctor if you have any unusual problems while receiving this medication.

Symptoms of overdose may include the following:
• blurred vision
• seeing things or hearing voices that do not exist (hallucinating)
• fever, sore throat, chills, or other signs of infection
• unusual bleeding or bruising
• black and tarry stools
• red blood in stools
• bloody vomit
• vomited material that looks like coffee grounds
• decreased urination
• swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
• sores in the mouth and throat
• seizures
• confusion
• coma (loss of consciousness for a period of time)

How should this medicine be used?

  • Ifosfamide comes as powder to be mixed with liquid to be injected over at least 30 minutes intravenously (into a vein) by a doctor or nurse in a medical facility.
  • It may be injected once a day for 5 days in a row.
  • This treatment may be repeated every 3 weeks.
  • The length of treatment depends on how well your body responds to treatment with ifosfamide.
  • Your doctor may need to delay your treatment if you experience certain side effects.
  • It is important for you to tell your doctor how you are feeling during your treatment with ifosfamide.

Other uses for this medicine

  • Ifosfamide is also sometimes used to treat bladder cancer, lung cancer, cancer of the ovaries (cancer that begins in the female reproductive organs where eggs are formed), cancer of the cervix, and certain types of soft tissue or bone sarcomas (cancer that forms in muscles and bones).
  • Talk to your doctor about the risks of using this medication for your condition.
  • This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.