Monthly Archives: August 2014

Key facts Ebola virus disease (EVD), formerly known as Ebola haemorrhagic fever, is a severe, often fatal illness in humans. EVD outbreaks have a case fatality rate of up to 90%. EVD outbreaks occur primarily in remote villages in Central and West Africa, near tropical rainforests. The virus is transmitted to people from wild animals and spreads in the human population through human-to-human transmission. Fruit bats of the Pteropodidae family are considered to be the natural host of the Ebola virus. Severely ill patients require intensive supportive care. No licensed specific treatment or vaccine is available for use in people or animals.

Hugely popular non-steroidal anti-inflammation drugs like aspirin, naproxen and ibuprofen all work by inhibiting or killing an enzyme called cyclooxygenase – a key catalyst in production of hormone-like lipid compounds called prostaglandins that are linked to a variety of ailments, from headaches and arthritis to menstrual cramps and wound sepsis. In a new paper, published this week in the online early edition of PNAS, researchers at the University of California, San Diego School of Medicine conclude that aspirin has a second effect: Not only does it kill cyclooxygenase, thus preventing production of the prostaglandins that cause inflammation and pain, it also prompts the enzyme to generate another compound that hastens […]

The medical organization Doctors Without Borders (MSF) today    released new evidence at the 6th South African AIDS Conference in  Durban on early success using the high-strength antibiotic, linezolid  as part of a treatment regimen for patients with extensively drug-  resistant tuberculosis (XDR-TB). This is some of the first clinical data  from both an African and primary care context suggesting that  linezolid is safe and effective for treating patients with XDR-TB,  including those co-infected with HIV. Despite growing rates of drug-resistant TB (DR-TB), and mounting global evidence on the effectiveness of linezolid in treating the disease, access to the drug in South Africa is limited due to high prices. However, […]

The 2014 Ebola outbreak is one of the largest Ebola outbreaks in history and the first in West Africa. It is affecting four countries in West Africa: Guinea, Liberia, Nigeria, and Sierra Leone, but does not pose a significant risk to the U.S. public. CDC is working with other U.S. government agencies, the World Health Organization, and other domestic and international partners in an international response to the current Ebola outbreak in West Africa. CDC has activated its Emergency Operations Center (EOC) to help coordinate technical assistance and control activities with partners. CDC has deployed several teams of public health experts to the West Africa region and plans to send […]