Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA https://tajando.com For a Healthier Tomorrow Tue, 06 Oct 2015 10:40:25 +0000 en-US hourly 1 https://wordpress.org/?v=5.5.3 Tuberculosis TB Initiative – TAJ PHARMA https://tajando.com/index.php/tuberculosis-tb-initiative-taj-pharma/ Thu, 05 Feb 2015 06:47:00 +0000 http://tajando.com/?p=3664 The post Tuberculosis TB Initiative – TAJ PHARMA appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>

The post Tuberculosis TB Initiative – TAJ PHARMA appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>
About Cancer – know your cancer — for everything from symptoms to coping after treatment https://tajando.com/index.php/about-cancer-know-your-cancer-for-everything-from-symptoms-to-coping-after-treatment/ Thu, 05 Feb 2015 06:44:25 +0000 http://tajando.com/?p=3662 The post About Cancer – know your cancer — for everything from symptoms to coping after treatment appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>

The post About Cancer – know your cancer — for everything from symptoms to coping after treatment appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>
Live Science features groundbreaking developments in science, space, technology – TAJ PHARMA https://tajando.com/index.php/live-science-features-groundbreaking-developments-in-science-space-technology-taj-pharma/ Thu, 05 Feb 2015 06:42:21 +0000 http://tajando.com/?p=3660 The post Live Science features groundbreaking developments in science, space, technology – TAJ PHARMA appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>

The post Live Science features groundbreaking developments in science, space, technology – TAJ PHARMA appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>
Manufacturing (GMP) in Europe – TAJ PHARMA https://tajando.com/index.php/manufacturing-gmp-in-europe-taj-pharma/ Thu, 05 Feb 2015 06:39:48 +0000 http://tajando.com/?p=3657 The post Manufacturing (GMP) in Europe – TAJ PHARMA appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>

The post Manufacturing (GMP) in Europe – TAJ PHARMA appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>
Ensure good dispensing practices for medicines- TAJ PHARMA https://tajando.com/index.php/3653/ Thu, 05 Feb 2015 06:35:26 +0000 http://tajando.com/?p=3653 The post Ensure good dispensing practices for medicines- TAJ PHARMA appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>

The post Ensure good dispensing practices for medicines- TAJ PHARMA appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>
Effervescent tablet – Improving drug administration – TAJ PHARMA https://tajando.com/index.php/effervescent-tablet-improving-drug-administration-taj-pharma/ Thu, 05 Feb 2015 06:32:20 +0000 http://tajando.com/?p=3651 The post Effervescent tablet – Improving drug administration – TAJ PHARMA appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>

The post Effervescent tablet – Improving drug administration – TAJ PHARMA appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>
Dispersible Tablets Many medicines are only available in adult strength; therefore the administratio https://tajando.com/index.php/dispersible-tablets-many-medicines-are-only-available-in-adult-strength-therefore-the-administratio/ Thu, 05 Feb 2015 06:27:44 +0000 http://tajando.com/?p=3649 Dispersible Tablets Many medicines are only available in adult strength; therefore the administratio – Taj Ando Pharmaceuticals, South Africa Dispersible Tablets Many medicines are only available in adult strength; therefore the administratio – Taj Ando Pharmaceuticals, South Africa Dispersible Tablets Many medicines are only available in adult strength; therefore the administratio – Taj Ando Pharmaceuticals, South Africa Dispersible Tablets Many medicines are only available in adult strength; therefore the administratio – Taj Ando Pharmaceuticals, South Africa

The post Dispersible Tablets Many medicines are only available in adult strength; therefore the administratio appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>

Dispersible Tablets Many medicines are only available in adult strength; therefore the administratio – Taj Ando Pharmaceuticals, South Africa
Dispersible Tablets Many medicines are only available in adult strength; therefore the administratio – Taj Ando Pharmaceuticals, South Africa
Dispersible Tablets Many medicines are only available in adult strength; therefore the administratio – Taj Ando Pharmaceuticals, South Africa
Dispersible Tablets Many medicines are only available in adult strength; therefore the administratio – Taj Ando Pharmaceuticals, South Africa

The post Dispersible Tablets Many medicines are only available in adult strength; therefore the administratio appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>
Safe Medication Practices – Always consult your doctor https://tajando.com/index.php/taj-ando-videos/ Thu, 05 Feb 2015 05:49:00 +0000 http://tajando.com/?p=3635 Safe Medication Practices – Always consult your doctor – Taj Ando Pharmaceuticals ,south africa | Tuberculosis TB Initiative TAJ PHARMA, Race Against Tuberculosis, deadly global epidemic of tuberculosis, current efforts to halt this airborne disease, world’s top TB physicians, scientists, advocates and policymakers, A world free of tuberculosis (TB); Safe Medication Practices – Always consult your doctor – Taj Ando Pharmaceuticals ,south africa | Tuberculosis TB Initiative TAJ PHARMA, Race Against Tuberculosis, deadly global epidemic of tuberculosis, current efforts to halt this airborne disease, world’s top TB physicians, scientists, advocates and policymakers, A world free of tuberculosis (TB); Safe Medication Practices – Always consult your doctor – Taj Ando Pharmaceuticals […]

The post Safe Medication Practices – Always consult your doctor appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>

Safe Medication Practices – Always consult your doctor – Taj Ando Pharmaceuticals ,south africa | Tuberculosis TB Initiative TAJ PHARMA, Race Against Tuberculosis, deadly global epidemic of tuberculosis, current efforts to halt this airborne disease, world’s top TB physicians, scientists, advocates and policymakers, A world free of tuberculosis (TB);
Safe Medication Practices – Always consult your doctor – Taj Ando Pharmaceuticals ,south africa | Tuberculosis TB Initiative TAJ PHARMA, Race Against Tuberculosis, deadly global epidemic of tuberculosis, current efforts to halt this airborne disease, world’s top TB physicians, scientists, advocates and policymakers, A world free of tuberculosis (TB);
Safe Medication Practices – Always consult your doctor – Taj Ando Pharmaceuticals ,south africa | Tuberculosis TB Initiative TAJ PHARMA, Race Against Tuberculosis, deadly global epidemic of tuberculosis, current efforts to halt this airborne disease, world’s top TB physicians, scientists, advocates and policymakers, A world free of tuberculosis (TB);
Safe Medication Practices – Always consult your doctor – Taj Ando Pharmaceuticals ,south africa | Tuberculosis TB Initiative TAJ PHARMA, Race Against Tuberculosis, deadly global epidemic of tuberculosis, current efforts to halt this airborne disease, world’s top TB physicians, scientists, advocates and policymakers, A world free of tuberculosis (TB);
Safe Medication Practices – Always consult your doctor – Taj Ando Pharmaceuticals ,south africa | Tuberculosis TB Initiative TAJ PHARMA, Race Against Tuberculosis, deadly global epidemic of tuberculosis, current efforts to halt this airborne disease, world’s top TB physicians, scientists, advocates and policymakers, A world free of tuberculosis (TB);
Safe Medication Practices – Always consult your doctor – Taj Ando Pharmaceuticals ,south africa | Tuberculosis TB Initiative TAJ PHARMA, Race Against Tuberculosis, deadly global epidemic of tuberculosis, current efforts to halt this airborne disease, world’s top TB physicians, scientists, advocates and policymakers, A world free of tuberculosis (TB);
Safe Medication Practices – Always consult your doctor – Taj Ando Pharmaceuticals ,south africa | Tuberculosis TB Initiative TAJ PHARMA, Race Against Tuberculosis, deadly global epidemic of tuberculosis, current efforts to halt this airborne disease, world’s top TB physicians, scientists, advocates and policymakers, A world free of tuberculosis (TB);

The post Safe Medication Practices – Always consult your doctor appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>
Can Avocados lower bad cholesterol? https://tajando.com/index.php/can-avocados-lower-bad-cholesterol/ Sat, 10 Jan 2015 11:29:34 +0000 http://tajando.com/?p=3179 Adding an avocado to your daily diet may help lower bad cholesterol, in turn reducing risk for heart disease, according to health researchers. Avocados are known to be a nutrient-dense food, high in monounsaturated fatty acids. Previous studies have suggested that avocados are a cholesterol-lowering food, but this is the first study – to the researchers’ knowledge – to look at health implications of avocados beyond monounsaturated fatty acids. “Including one avocado each day as part of a moderate-fat, cholesterol-lowering diet compared to a comparable moderate-fat diet without an avocado provides additional LDL (low-density lipoproteins) lowering affects, which benefit CVD risk,” said Penny M. Kris-Etherton, Distinguished Professor of Nutrition. Kris-Etherton […]

The post Can Avocados lower bad cholesterol? appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>

Adding an avocado to your daily diet may help lower bad cholesterol, in turn reducing risk for heart disease, according to health researchers. Avocados are known to be a nutrient-dense food, high in monounsaturated fatty acids.

Previous studies have suggested that avocados are a cholesterol-lowering food, but this is the first study – to the researchers’ knowledge – to look at health implications of avocados beyond monounsaturated fatty acids.

“Including one avocado each day as part of a moderate-fat, cholesterol-lowering diet compared to a comparable moderate-fat diet without an avocado provides additional LDL (low-density lipoproteins) lowering affects, which benefit CVD risk,” said Penny M. Kris-Etherton, Distinguished Professor of Nutrition.

Kris-Etherton and colleagues tested three different diets, all designed to lower cholesterol: a lower-fat diet, consisting of 24 percent fat, and two moderate fat diets, with 34 percent fat. The moderate fat diets were nearly identical, however one diet incorporated one Hass avocado every day while the other used a comparable amount of high oleic acid oils – such as olive oil – to match the fatty acid content of one avocado. Hass avocados are the smaller, darker variety with bumpy green skin and have a higher nutrient content than Florida avocados, which are larger, and have smoother skin and a higher water content.

The researchers tested the diets with 45 healthy, overweight adults between the ages of 21 and 70. Compared to the participants’ baseline measurements, all three diets significantly lowered LDL – also known as bad cholesterol – as well as total cholesterol. However, participants experienced an even greater reduction in LDL and total cholesterol while on the avocado diet, compared to the other two diets, the researchers report (Jan. 7) in the Journal of the American Heart Association.

The avocado diet decreased bad cholesterol by 13.5 mg/dL, while LDL was decreased by 8.3 mg/dL on the moderate-fat diet and by 7.4 mg/dL on the low-fat diet.

All participants followed each of the three diets for five weeks. They were given a two-week break in between each diet. Blood samples were taken at the beginning and end of each study period. Subjects were randomly assigned the order in which they received each diet.

“This was a controlled feeding study, but that is not the real world – so it is more of a proof-of-concept investigation,” said Kris-Etherton. “We need to focus on getting people to eat a healthy diet that includes avocados and other food sources of better fats.”

She pointed out that much of the U.S. population doesn’t know how to use or prepare avocados, with the exception of guacamole. However, guacamole is usually eaten with corn chips, which are high in both sodium and calories.

“People should start thinking about eating avocados in new ways,” said Kris-Etherton. “I think using it as a condiment is a great way to incorporate avocados into meals – for instance, putting a slice or two on a sandwich or using chopped avocado in a salad or to season vegetables.”

Kris-Etherton and colleagues note that further research will need to be conducted with a larger and more diverse study sample and to explore further how high-density lipoproteins – good cholesterol – might be affected by a diet that includes avocados.

Can Avocados lower bad cholesterol? – Taj Ando Pharmaceuticals, South Africa | Adding an avocado to your daily diet may help lower bad cholesterol, in turn reducing risk for heart disease, according to health researchers. Avocados are known to be a nutrient-dense food, high in monounsaturated fatty acids.
Can Avocados lower bad cholesterol? – Taj Ando Pharmaceuticals, South Africa | Adding an avocado to your daily diet may help lower bad cholesterol, in turn reducing risk for heart disease, according to health researchers. Avocados are known to be a nutrient-dense food, high in monounsaturated fatty acids.
Can Avocados lower bad cholesterol? – Taj Ando Pharmaceuticals, South Africa | Adding an avocado to your daily diet may help lower bad cholesterol, in turn reducing risk for heart disease, according to health researchers. Avocados are known to be a nutrient-dense food, high in monounsaturated fatty acids.
Can Avocados lower bad cholesterol? – Taj Ando Pharmaceuticals, South Africa | Adding an avocado to your daily diet may help lower bad cholesterol, in turn reducing risk for heart disease, according to health researchers. Avocados are known to be a nutrient-dense food, high in monounsaturated fatty acids.

The post Can Avocados lower bad cholesterol? appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>
Killing cancer cells with promising new therapy https://tajando.com/index.php/killing-cancer-cells-with-promising-new-therapy/ Mon, 05 Jan 2015 23:35:38 +0000 http://tajando.com/?p=3181 Cell biologists at UT Southwestern Medical Center have targeted telomeres with a small molecule called 6-thiodG that takes advantage of the cell’s ‘biological clock’ to kill cancer cells and shrink tumor growth. Dr. Jerry W. Shay, Professor and Vice Chairman of Cell Biology at UT Southwestern, and colleague, Dr. Woodring E. Wright, Professor of Cell Biology and Internal Medicine, found that 6-thio-2′-deoxyguanosine could stop the growth of cancer cells in culture and decrease the growth of tumors in mice. “We observed broad efficacy against a range of cancer cell lines with very low concentrations of 6-thiodG, as well as tumor burden shrinkage in mice,” said Dr. Shay, Associate Director of […]

The post Killing cancer cells with promising new therapy appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>

Cell biologists at UT Southwestern Medical Center have targeted telomeres with a small molecule called 6-thiodG that takes advantage of the cell’s ‘biological clock’ to kill cancer cells and shrink tumor growth.

Dr. Jerry W. Shay, Professor and Vice Chairman of Cell Biology at UT Southwestern, and colleague, Dr. Woodring E. Wright, Professor of Cell Biology and Internal Medicine, found that 6-thio-2′-deoxyguanosine could stop the growth of cancer cells in culture and decrease the growth of tumors in mice.

“We observed broad efficacy against a range of cancer cell lines with very low concentrations of 6-thiodG, as well as tumor burden shrinkage in mice,” said Dr. Shay, Associate Director of the Harold C. Simmons Comprehensive Cancer Center.

Dr. Shay and Dr. Wright, who hold The Southland Financial Corporation Distinguished Chair in Geriatrics, are co-senior authors of the paper appearing in the journal Cancer Discovery.

6-thiodG acts by targeting a unique mechanism that is thought to regulate how long cells can stay alive, a type of aging clock. This biological clock is defined by DNA structures known as telomeres, which cap the ends of the cell’s chromosomes to protect them from damage, and which become shorter every time the cell divides. Once telomeres have shortened to a critical length, the cell can no longer divide and dies though a process known as apoptosis.

Cancer cells are protected from this death by an RNA protein complex called telomerase, which ensures that telomeres do not shorten with every division. Telomerase has therefore been the subject of intense research as a target for cancer therapy. Drugs that successfully block its action have been developed, but these drugs have to be administered for long periods of time to successfully trigger cell death and shrink tumors, leading to considerable toxicities. This outcome is partially because cells in any one tumor have chromosomes with different telomere lengths and any one cell’s telomeres must be critically shortened to induce death.

6-thiodG is preferentially used as a substrate by telomerase and disrupts the normal way cells maintain telomere length. Because 6-thiodG is not normally used in telomeres, the presence of the compound acts as an ‘alarm’ signal that is recognized by the cell as damage. As a result, the cell stops dividing and dies.

Telomerase is an almost universal oncology target, yet there are few telomerase-directed therapies in human clinical trials, researchers noted.

“Using telomerase to incorporate toxic products into telomeres is remarkably encouraging at this point,” said Dr. Wright.

Importantly, unlike many other telomerase-inhibiting compounds, the researchers did not observe serious side effects in the blood, liver and kidneys of the mice that were treated with 6-thiodG.

“Since telomerase is expressed in almost all human cancers, this work represents a potentially innovative approach to targeting telomerase-expressing cancer cells with minimal side effects on normal cells,” said Dr. Shay. “We believe this small molecule will address an unmet cancer need in an underexplored area that will be rapidly applicable to the clinic.”

Killing cancer cells with promising new therapy – Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA| Cell biologists at UT Southwestern Medical Center have targeted telomeres with a small molecule called 6-thiodG that takes advantage of the cell’s ‘biological clock’ to kill cancer cells and shrink tumor growth.
Killing cancer cells with promising new therapy – Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA| Cell biologists at UT Southwestern Medical Center have targeted telomeres with a small molecule called 6-thiodG that takes advantage of the cell’s ‘biological clock’ to kill cancer cells and shrink tumor growth.
Killing cancer cells with promising new therapy – Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA| Cell biologists at UT Southwestern Medical Center have targeted telomeres with a small molecule called 6-thiodG that takes advantage of the cell’s ‘biological clock’ to kill cancer cells and shrink tumor growth.

The post Killing cancer cells with promising new therapy appeared first on Taj Ando Pharmaceuticals, South Africa, TAJ PHARMA.

]]>