Etoposide Injection

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What is Etoposide Injection?

Etoposide injection is used in combination with other medications to treat cancer of the testicles that has not improved or that has worsened after treatment with other medications or radiation therapy.
Etoposide injection is also used in combination with other medications to treat a certain type of lung cancer (small cell lung cancer; SCLC).
Etoposide is in a class of medications known as podophyllotoxin derivatives.
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Special Precautions

Before receiving etoposide injection,
• tell your doctor and pharmacist if you are allergic to etoposide, etoposide phosphate (Etopophos), any other medications, or any of the ingredients in etoposide or etoposide phosphate injection. Ask your pharmacist for a list of the ingredients.
• tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
Be sure to mention any of the following:
cisplatin (Platinol),cyclosporine (Gengraf, Neoral, Sandimmune).

Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
Many other medications may also interact with etoposide, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
• tell your doctor if you have or have ever had kidney disease.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding.
You should not become pregnant or breast-feed while you are receiving etoposide injection.
If you become pregnant while receiving etoposide injection, call your doctor.
Etoposide may harm the fetus.

Side Effects

Etoposide injection may cause side effects.
Tell your doctor if any of these symptoms are severe or do not go away:
• swelling, pain, redness, or burning at the injection site
• nausea
• vomiting
• sores in the mouth and throat
• stomach pain
• diarrhea
• constipation
• loss of appetite or weight
• unusual tiredness or weakness
• pale skin
• fainting
• dizziness
• hair loss
• pain, burning, or tingling in the hands or feet
• eye pain

Serious side effects.
If you experience any of these symptoms call your doctor immediately or get emergency medical treatment:
• rash
• hives
• itching
• difficulty breathing or swallowing
• fast, irregular, or pounding heartbeat
• seizures
• yellowing of the skin or eyes

How is Etoposide Injection given?

Etoposide is injected into a vein through an IV. A healthcare provider will give you this injection.

Etoposide is usually given as part of a 4-day or 5-day treatment cycle every 3 or 4 weeks. Follow your doctor’s dosing instructions very carefully.

Etoposide can be harmful if it gets on your skin. If skin contact occurs, wash the area with soap and water.

Etoposide can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests.