Lamivudine Tablets



Lamivudine tablets belongs to a group of antiviral medicines, also known as antiretrovirals,
called nucleoside analogue reverse transcriptase inhibitors (NRTIs).
These are used to treat Human Immunodeficiency Virus (HIV) infection.

Lamivudine tablets is used in antiretroviral combination therapy for the treatment of HIV infection.
Lamivudine tablets reduces the amount of HIV virus in your body, and keeps it at a low level.

It also increases CD4 cell counts. CD4 cells are a type of white blood cell that plays an
important role in maintaining a healthy immune system to help fight infection.
Response to treatment with Lamivudine tablets varies between patients. Your doctor or health care provider will be monitoring the effectiveness of your treatment.

Lamivudine tablets may improve your condition, but it is not a cure for your HIV infection.
HIV infection is a disease spread by contact with blood or sexual contact with an infected individual.
Treatment with Lamivudine tablets has not been shown to reduce the risk of passing HIV infection on to others by sexual contact or by blood transfer. Therefore, you must continue to take appropriate precautions to avoid giving the virus to others.

During your treatment, other infections linked to your weakened immunity (opportunistic infections)
may arise. These will require specific and sometimes preventive treatment.Lamivudine Tablets – Taj Ando Pharmaceuticals, South Africa | Lamivudine tablets belongs to a group of antiviral medicines, also known as antiretrovirals,called nucleoside analogue reverse transcriptase inhibitors (NRTIs).These are used to treat Human Immunodeficiency Virus (HIV) infection.


  • Like all medicines, Lamivudine tablets can cause side effects, although not everybody gets them.
  • When treating HIV infection, it is not always possible to differentiate between unwanted effects caused by Lamivudine tablets or those caused by any other medicines you may be taking at the same time, or by the HIV disease. For this reason, it is important that you inform your doctor or health care provider of any change in your health.
  • Short-term adverse reactions to combination antiretroviral therapy are common.
  • After you start taking Lamivudine tablets headache, nausea and vomiting, abdominal pain, diarrhoea and fatigue may occur: these reactions are usually mild and disappear within a few weeks even if treatment is

Commonly reported (greater than 1 in every 100 patients treated) side effects are

  • fatigue
  • headache
  • insomnia
  • nausea
  • abdominal pain
  • diarrhoea and hair loss.

The following side effects are uncommon (between 1 in 1,000 and 1 in 100 patients treated):

  • decrease of white blood cells.
  • Combination antiretroviral therapy may cause a condition called lactic acidosis, which is a build up of lactic acid in the body, that can cause dehydration and coma.
  • These reactions have been reported on rare occasions in patients taking NRTIs.
  • Deep, rapid breathing, drowsiness, and non specific symptoms such as nausea, vomiting and stomach pain, may indicate the development of lactic acidosis.
  • Combination antiretroviral therapy may cause changes in body shape due to changes in fat distribution.
  • These may include loss of fat from legs, arms and face, increased fat in the abdomen(belly) and other internal organs, breast enlargement and fatty lumps on the back of the neck (‘buffalo hump’).
  • The cause and long-term health effects of these conditions are not known at this time.
  • Combination antiretroviral therapy may also cause raised lactic acid and sugar in the blood,hyperlipaemia (increased fats in the blood) and resistance to insulin.