Tacrolimus Capsules

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What are Tacrolimus Capsules?

Tacrolimus capsules are a prescription medicine used with other medicines to help prevent organ rejection in people who have had a kidney, liver, or heart transplant and tacrolimus capsules are not for use with medicines called cyclosporines (Gengraf®, Neoral®, and Sandimune®).

Tacrolimus capsules are not for use with a medicine called sirolimus (Rapamune®) in people who have had a liver or heart transplant.

It is not known if tacrolimus capsules are safe and effective when used with sirolimus in people who have had kidney transplants.

It is not known if tacrolimus capsules are safe and effective in children who have had a kidney or heart transplant.Tacrolimus Capsules – Taj Ando Pharmaceuticals, South Africa | Tacrolimus capsules are a prescription medicine used with other medicines to help prevent organ rejection in people who have had a kidney, liver, or heart transplant and tacrolimus capsules are not for use with medicines called cyclosporines (Gengraf®, Neoral®, and Sandimune®). Tacrolimus Capsules – Taj Ando Pharmaceuticals, South Africa | Tacrolimus capsules are a prescription medicine used with other medicines to help prevent organ rejection in people who have had a kidney, liver, or heart transplant and tacrolimus capsules are not for use with medicines called cyclosporines (Gengraf®, Neoral®, and Sandimune®). Tacrolimus Capsules – Taj Ando Pharmaceuticals, South Africa | Tacrolimus capsules are a prescription medicine used with other medicines to help prevent organ rejection in people who have had a kidney, liver, or heart transplant and tacrolimus capsules are not for use with medicines called cyclosporines (Gengraf®, Neoral®, and Sandimune®). Tacrolimus Capsules – Taj Ando Pharmaceuticals, South Africa | Tacrolimus capsules are a prescription medicine used with other medicines to help prevent organ rejection in people who have had a kidney, liver, or heart transplant and tacrolimus capsules are not for use with medicines called cyclosporines (Gengraf®, Neoral®, and Sandimune®). Tacrolimus Capsules – Taj Ando Pharmaceuticals, South Africa | Tacrolimus capsules are a prescription medicine used with other medicines to help prevent organ rejection in people who have had a kidney, liver, or heart transplant and tacrolimus capsules are not for use with medicines called cyclosporines (Gengraf®, Neoral®, and Sandimune®).

Tacrolimus Capsules can cause SERIOUS SIDE EFFECTS, including:

1. Increased risk of cancer. People who take tacrolimus capsules have an increased risk of getting some kinds of cancer, including skin and lymph gland cancer (lymphoma).

2.Increased risk of infection. Tacrolimus capsules are a medicine that affects your immune system. Tacrolimus capsules can lower the ability of your immune system to fight infections.

3.Serious infections can happen in people receiving tacrolimus capsules that can cause death. Call your doctor right away if you have symptoms of an infection such as:

  • fever
  • sweats or chills
  • cough or flu-like symptoms
  • muscle aches
  • warm, red, or painful areas on your skin

Possible Side Effects of Tacrolimus Capsules?

  • high blood sugar (diabetes).
  • Your doctor may do certain tests to check for diabetes while you take tacrolimus capsules. Call your doctor right away if you have:
    1) frequent urination,2) increased thirst or hunger,3) blurred vision,4) confusion,5) drowsiness,6) loss of appetite,7) fruity smell on your breath,
    8) nausea, vomiting, or stomach pain
  • kidney problems.
    — Your doctor may do certain tests to check your kidney function while you take tacrolimus capsules.
  • nervous system problems.
    — Call your doctor right away if you get any of these symptoms while taking tacrolimus capsules. These could be signs of a serious nervous system problem:1) confusion,2) coma,3) muscle tremors,4) numbness and tinglin,
    5) headache,6) seizures,7) vision changes
  • high levels of potassium in your blood.
    — Your doctor may do certain tests to check your potassium level while you take tacrolimus capsules.
  • high blood pressure.
    — Your doctor will monitor your blood pressure while you take tacrolimus capsules.
  • heart problems (myocardial hypertrophy).
    — Tell your doctor right away if you get any of these symptoms of heart problems while taking tacrolimus capsules: shortness of breath,chest pain,feel lightheaded,feel faintThe most common side effects of Tacrolimus Capsules in people receiving kidney transplant are:
  • infection
  • tremors (shaking of the body)
  • high blood pressure
  • kidney problems
  • constipation
  • diarrhea
  • headache
  • stomach pain
  • trouble sleeping
  • nausea,low levels of phosphate in your blood
  • swelling of the hands, ankles, or legs
  • weakness,pain
  • high levels of fat in your blood
  • high levels of potassium in your blood
  • low red blood cell count (anemia)
  • The most common side effects of Tacrolimus Capsules in people receiving liver transplants are:
  • shaking of the body tremors
  • headache,diarrhea,high blood pressure,nausea
  • kidney problems,stomach pain,trouble sleeping
  • numbness or tingling in your hands or feet
  • anemia,pain,fever,weakness
  • high levels of potassium in the blood
  • low levels of magnesium in the blood
  • The most common side effects of tacrolimus capsules for heart transplant patients are:
  • kidney problems
  • high blood pressure

Before you take Tacrolimus Capsules, tell your doctor if you:

  • plan to receive any live vaccines
  • have or have had liver, kidney or heart problems
  • are pregnant or plan to become pregnant.
  • Tacrolimus capsules may harm your unborn baby.
  • Talk to your doctor if you are pregnant or plan to become pregnant.
  • Are breastfeeding or plan to breastfeed.
  • Tacrolimus capsules can pass into your breast milk.

Especially tell your doctor if you take:

  • cyclosporine (Gengraf®, Neoral®, and Sandimune®)
  • sirolimus (Rapamune®)
  • nelfinavir (Viracept®)
  • telaprevir (Incivek™)
  • boceprevir (Victrelis™)
  • amiodarone (Cordarone™, Nexterone™, Pacerone™)

Tacrolimus capsules may affect the way other medicines work, and other medicines may affect how tacrolimus capsules works.

How should I store Tacrolimus Capsules?

  • Store tacrolimus capsules at 20° to 25°C (68° to 77° F).
  • Safely throw away medicine that is out of date or no longer needed.
  • Keep Tacrolimus Capsules and all medicines out of reach of children.