Vincristine Injection

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WHAT VINCRISTINE INJECTION IS AND WHAT IT IS USED FOR

Vincristine is an anti-cancer medicine.Treatment with an anti-cancer medicine is sometimes called cancer chemotherapy.
Vincristine Injection is used in the treatment of cancers of the blood (eg.leukaemia or lymphomas), breast, head and neck or lung. It may be used to treat multiple myeloma (a cancer of plasma cells) and it may also be used in the treatment of some cancers in children. It may be used in a blood disorder known as idiopathic thrombocytopenic purpura (ITP) after other treatments have not been successful.
Vincristine Injection may be given alone or in combination with other anti-cancer medicines.Vincristine Injection – Taj Ando Pharmaceuticals, South Africa | Vincristine is an anti-cancer medicine.Treatment with an anti-cancer medicine is sometimes called cancer chemotherapy.Vincristine Injection is used in the treatment of cancers of the blood (eg.leukaemia or lymphomas), breast, head and neck or lung.Vincristine Injection – Taj Ando Pharmaceuticals, South Africa | Vincristine is an anti-cancer medicine.Treatment with an anti-cancer medicine is sometimes called cancer chemotherapy.Vincristine Injection is used in the treatment of cancers of the blood (eg.leukaemia or lymphomas), breast, head and neck or lung.Vincristine Injection – Taj Ando Pharmaceuticals, South Africa | Vincristine is an anti-cancer medicine.Treatment with an anti-cancer medicine is sometimes called cancer chemotherapy.Vincristine Injection is used in the treatment of cancers of the blood (eg.leukaemia or lymphomas), breast, head and neck or lung.

POSSIBLE SIDE EFFECTS

  • Like all medicines, vincristine can have side effects, although not everybody gets them.
  • If any of the following happen, tell your doctor immediately:
  • severe allergic reaction – you may experience a sudden itchy rash (hives), swelling of the hands, feet, ankles, face, lips, mouth or throat (which may cause difficulty in swallowing or breathing), and you may feel you are going to faint.
  • pain or swelling at the injection site during or immediately after the injection
  • severe chest pains possibly radiating to the jaw or arm, sweating,
    breathlessness and nausea severe breathing problems

These are serious side effects. You may need urgent medical attention. All of these serious side effects are rare.

  • If any of the following happen, tell your doctor as soon as possible:
  • convulsions (fits),deafness or hearing loss,worsening eyesight
  • pain (may involve the jaw, throat, neck, bones or muscles)
  • dizziness,significant weight loss
  • fever, sore throat, skin rashes, or sores on your body and in your mouth (may indicate a drop in white blood cells)
  • numbness or pins and needles,difficulty in walking
  • muscle weakness or muscle wasting
  • difficulty with speech,unusual eye movements
  • problems with passing water (more or less urine than normal, or pain when passing urine)
  • mild breathing problems,raised or lowered blood pressure
  • headache,tiredness,unexpected bruises
  • stomach cramps, constipation or diarrhoea
  • being sick or feeling sick,hair loss
  • missed periods
  • soreness around the injection site after the injection

* Vincristine sulphate may lead to changes in your blood cells. Your doctor may take blood samples to monitor for these and also to check how well your liver is working.

* If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor.

Effects on fertility

  • Treatment with vincristine sulphate may permanently reduce fertility in men and women. Tell your doctor if you have concerns.

HOW TO STORE VINCRISTINE INJECTION

  • Keep out of the reach and sight of children

Expiry

  • This medicine must not be used after the expiry date which is stated on the vial label and carton after ‘EXP’.
  • Where only a month and year is stated, the expiry date refers to the last day of that month.

Storage

  • The vials should be kept in the outer carton, in order to protect from light, and stored in a refrigerator.