CAS number 137234-62-9 Voriconazolea Triazole antifungal agent, is available as a lyophilized powder for solution for intravenous infusion, film-coated tablets for oral administration, and as a powder for oral suspension. Voriconazole is designated chemically as (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4- pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol with an empirical formula of C16H14F3N5O and a molecular weight of 349.3. Voriconazole drug substance is a white to light-colored powder. FormulaStructure :
Voriconazole Formula Structure
Systematic (IUPAC) name (2R,3S)-2-(2,4-difluorophenyl)-3- (5-fluoropyrimidin-4-yl)-1- (1H-1,2,4-triazol-1-yl) butan-2- ol Identifiers CAS number 137234-62-9 ATC code J02AC03 PubChem 71616 DrugBank APRD00543 Chemical data Formula C16H14F3N5O Mol. mass 349.311 g/mol Pharmacokinetic data Bioavailability 96% Protein binding 58% Metabolism Hepatic cytochrome P450 enzymes CYP2C19, CYP2C9, CYP3A4 Half life Dose-dependent Excretion Therapeutic considerations Pregnancy cat. D Legal status Prescription only Routes IV, oral
Voriconazole API – Taj Ando Pharmaceuticals, South Africa | Voriconazolea Triazole antifungal agent, is available as a lyophilized powder for solution for intravenous infusion, film-coated tablets for oral administration, and as a powder for oral suspension. Voriconazole is designated chemically as (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4- pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol with an empirical formula of C16H14F3N5O and a molecular weight of 349.3. Voriconazole drug substance is a white to light-colored powder. Voriconazole API – Taj Ando Pharmaceuticals, South Africa | Voriconazolea Triazole antifungal agent, is available as a lyophilized powder for solution for intravenous infusion, film-coated tablets for oral administration, and as a powder for oral suspension. Voriconazole is designated chemically as (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4- pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol with an empirical formula of C16H14F3N5O and a molecular weight of 349.3. Voriconazole drug substance is a white to light-colored powder.
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